Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages
نویسندگان
چکیده
منابع مشابه
Remodeling phenotype of human subcutaneous adipose tissue macrophages.
BACKGROUND Adipose tissue macrophages (ATMs) have become a focus of attention recently because they have been shown to accumulate with an increase in fat mass and to be involved in the genesis of insulin resistance in obese mice. However, the phenotype and functions of human ATMs are still to be defined. METHODS AND RESULTS The present study, performed on human subcutaneous AT, showed that AT...
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Adipose tissue (AT) is a very important endocrine and paracrine organ that regulates oth‐ er tissues and organs. Dysfunction of AT leads to a wide range of disorders like obesity, insulin resistance, diabetes mellitus, cardiac disorders, tumors and others. Adipose tissue macrophages (ATMs) are the key actors in AT remodeling and dysfunction. Their role in AT dysfunction is nowadays increasingly...
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The developments in the technologies based on the use of autologous adipose tissue attracted attention to minor depots as possible sampling areas. Some of those depots have never been studied in detail. The present study was performed on subcutaneous adipose depots sampled in different areas with the aim of explaining their morphology, particularly as far as regards stem niches. The results dem...
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1. Autoimmunity & Transplantation Division, Walter & Eliza Hall Institute of Medical Research, 1 G Royal Parade, Parkville 3050, Victoria, Australia 2. Burnet Clinical Research Unit, Royal Melbourne Hospital, Grattan Street, Parkville 3050, Victoria, Australia 3. Centre for Obesity Research and Education, Monash University, Commercial Road, Prahran 3181, Victoria, Australia 4. Bioinformatics Di...
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I. Adipose tissue was obtained simultaneously from subcutaneous and deep sites in children undergoing elective surgery, and from different subcutaneous sites in adults. The lipid content and fatty acid composition were measured using gas-liquid chromatography and the number of cells counted after fixation in osmium tetroxide. The mean amount of lipid per cell was used as a measure of the size o...
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ژورنال
عنوان ژورنال: Circulation
سال: 2008
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.107.724096